Physicochemical, Phytochemical and Gcms Analysis of Siddha Medicine Peenisa Chooranam in the Treatment of azhal Thalainokkadu

Abstract

Azhal Thalainokkadu is a disease that can be correlated with the signs and symptoms of rhinitis, headache, pain in the ears and pain over the sinuses. Peenisa Chooranam (PC) is indicated in the dosage of Verukadi alavu (1.5 grams) for 28 days with the anubhanam lukewarm water for the conditions Peenisangal, Nasi naatram and Nasi raththam. To ensure the quality and efficacy, standardisation of the medicines is essential. In such a way that the present study attempts to provide insight into the preliminary analyses.

Place of study: The studies Physico-Chemical analysis, Phytochemical analysis and GCMS analysis of PC were performed at Analytical chemistry lab, Research and Developmental Wing for ISM, AAGHIM campus, Arumbakkam, Chennai - 106.

Methodology: The study medicine Peenisa Chooranam (PC) was prepared as per the literature, study as performed as per PLIM guidelines and results were analysed.

Result: Brown-coloured dried powder shows the correct ingredients as per the literature. Physicochemical analysis shows 06.50% of the total ash value, 03.90% moisture content, and 5.47 pH. Phytochemical analysis shows the presence of alkaloids, flavonoids, glycosides, lignin and other constituents. GCMS analysis shows the presence of piperine with the highest peak area percentage, followed by other compounds.

Conclusion: From this study it is concluded that the study is evidence of quality of formulation and preparation with its active constituents. It can be used to evaluate the authenticity of Peenisa Chooranam to further quality content research with recent analytical tools.