ASSESSMENT OF HEALTH-RELATED QUALITY OF LIFE, ANXIETY AND DEPRESSION IN PATIENTS WITH RHEUMATOID ARTHRITIS
Abstract
In an attempt our study was to assess health-related quality of life, anxiety & depression among patients with Rheumatoid arthritis. In this study demonstrates that the Rheumatoid arthritis patients evaluated were more likely to have lower Quality of Life, and high prevalence rates of depression and anxiety, the factors leading to an increased risk of depression among Rheumatoid arthritis patients included being female and older. As depression is the one of the major factor for medication non adherence ,So it could be better if Rheumatoid arthritis patients should be regularly assessed and should be monitored for accompanying anxiety and depression during follow-up, to achieve better therapeutic outcome, and to improve patient Quality of Life. We are taking Out of 50 patients, both men and women. It is a six months observational prospective cohort study conducted at King George Hospital, we have to assess the healthrelated quality of life in patients with RA along with Anxiety and depression in these who are patients suffering with Rheumatoid arthritis. In the data was collected from the direct patient-reported survey, and we are analysed the data by using the Microsoft excel spread sheet along with, Hamilton Rating Scale for Depression HAM-D, Hamilton Anxiety Rating Scale (HAM-A) and we are taken informed consent forms and with proper compliance and age greater than 18 years those who are positively diagnosed with rheumatoid arthritis.
Keywords:
Rheumatoid arthritis, Case study, six months, 50 Patient, Quality Of Life, Anxiety & Depression, Hamilton Rating Scale for DepressionReferences
Joseph T. Dipiro, Robert L. Talbert; Pharmacotherapy A Pathophysiologic Approach 6th ed: New York; McGraw-Hill; 2008 pg.no 1532 Available at: http://www.news-edical.net/health/Rheumatoid-ArthritisHistory.aspx (Accessed on 04-09-2016).
Schiff M. Emerging treatments for rheumatoid arthritis. Am J Med 102 (1 Suppl):11S–15S, 1997.
Smith JB, Haynes MK. Rheumatoid arthritis—A molecular under-standing. Ann Intern Med. 2002;136(12):908–922.2.
Klippel JH CL, Stone JH, Weyand CM, eds. Primer on the Rheumatic Diseases, 12th ed. Atlanta, GA: Arthritis Foundation, 2001.3.
Harris ED. The clinical features of rheumatoid arthritis. In: Harris ED,Budd RC, Firestein GS, et al, eds. Textbook of Rheumatology, 7th ed.Philadelphia: Elsevier/Saunders, 2005:1043–1078.
Shibue T, Tsuchiya N, Komata T, et al. Tumor necrosis factor alpha 5′-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. Arthritis Rheum 43:753–757, 2000.
Jiang H, Chess L. Regulation of immune response by T cells. N Engl JMed 2006;354:1166–1176.
Tsokos GC. B cells, be gone—B-cell depletion in the treatment of rheumatoid arthritis. N Engl J Med 2004;350(25):2546–2548.
Weinstein E, Peeva E, Putterman C, Diamond B. B-cell biology. Rheum Dis Clin North Am 2004;30(1):159–174.
Choy EH, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001;344(12):907–916.
Arend WP. Physiology of cytokine pathways in rheumatoid arthritis. Arthritis Care Res 2001;45:101–106.
Choy E, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001;344:907–916.
Firestein GS. Etiology and pathogenesis of rheumatoid arthritis. In:Harris ED, Budd RC, Firestein GS, eds. Textbook of Rheumatology,7th ed. Philadelphia: Elsevier/Saunders, 2005:996–1042.
Meyer FA, Yaron I, Yaron M. Synergistic, additive, and antagonistic effects of interleukin-1β, tumor necrosis factor α, and δ-interferon on prostaglandin E, hyaluronic acid, and collagenase production by cultured synovial fibroblasts. Arthritis Rheum 33:1518–1525, 2000.
Hard ER. Extra articular manifestations of rheumatoid arthritis. SeminArthritis Rheum 1979;8:151–176.
Choi HK, Hernan MA, Seeger JD, et al. Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study. Lancet2002;359:1173–1177.
Wallberg-Jonsson S, Johansson H, Ohman ML, Rantapaa-Dahlqvist S.Extent of inflammation predicts cardiovascular disease and overall mortality in seropositive rheumatoid arthritis. A retrospective cohort study from disease onset. J Rheumatol 1999;26(12):2562–2571.
American College of Rheumatology Subcommittee on Rheumatoid Arthritis G. Guidelines for the management of rheumatoid arthritis:2002 Update. Arthritis Rheum 2002;46(2):328–346.
Chan KA, Felson DT, Yood RA, et al. The lag time between onset of symptoms and diagnosis of rheumatoid arthritis. Arthritis Rheum 37:814–820, 1994.
Katz PP, Yelin EH. The development of depressive symptoms among women with rheumatoid arthritis. Arthritis Rheum 38:49– 56, 1995.
Escalante A, del Rincon I, Mulrow CD. Symptoms of depression and psychological distress among Hispanics with rheumatoid arthritis. Arthritis Care Res 13:156–167, 2000.
Parker JC, Smarr KL, Slaughter JR, et al. Management of depression in rheumatoid arthritis: a combined pharmacologic and cognitive-behavioral approach. Arthritis Rheum 49:766–777, 2003.
Joseph T. Dipiro, Robert L. Talbert; Pharmacotherapy A Pathophysiologic Approach 6th ed: New York; McGraw-Hill; 2008 pg.no 1543.
Joseph T. Dipiro, Robert L. Talbert; Pharmacotherapy A Pathophysiologic Approach 6th ed: New York; McGraw-Hill; 2008 pg.no 1544.
2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis JASVINDER A. SINGH,1 et al. 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis , published in Arthritis & Rheumatology on 2015.
Availableat:http://www.medscape.com/viewarticle/851247 accessed on 12-10-2016.
Availableat:http://www.assessmentpsychology.com/HAM-A-scoring.pdf accessed on 12-10-2016.
D. WHALLEY, S. P. McKENNA, Z. DE JONG and D. VAN DER HEIJDE QUALITY OF LIFE IN RHEUMATOID ARTHRITIS British Journal of Rheumatology 1997;36:884–888.
Ruta DA, Hurst NP, Kind P, Hunter M, Stubbings A. Measuring health status in British patients with rheumatoid arthritis: reliability, validity and responsiveness of the short form 36-item health survey (SF-36). Br J Rheumatol. 1998 Apr;37(4):425–436
Sokoll KB, Helliwell PS. Comparison of disability and quality of life in rheumatoidand psoriatic arthritis Aug;28(8):1842-6.
Esam Mohammed Abu Al-Fadla, , , Mohammed Ali Ismaila, Mohammed Thabitb, Yasser El-Serogy Assessment of health-related quality of life, anxiety and depression in patients with early rheumatoid arthritis Volume 36, Issue 2, April 2014, Pages 51–56.
A.J. Mathew, J. Antony, S. Eremenco, B.V. Paul, B. Jayakumar, J. Philip Health-related quality of life in rheumatoid arthritis patients in South India Singapore Med J, 50 (8) (2009), pp. 800–803.
T. K. Kvien & T. Uhlig Quality of life in rheumatoid arthritis Volume 34, 2005 - Issue 5.
Hawley DJ , Wolfe F Anxiety and depression in patients with rheumatoid arthritis: a prospective study of 400 patients The Journal of Rheumatology [1988, 15(6):932-941].
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