Formulation and evaluation of antiarthritic herbal chocolate: a review

Authors

  • Badri. Sireesha Associate Professor, Dr. Samuel George Institute Of Pharmaceutical Sciences Tarlupadu Road ,Markapur , Prakasam dt. Pin code 523316
  • D. Smily B. Pharmacy. Dr. Samuel George Institute Of Pharmaceutical Sciences Tarlupadu Road ,Markapur , Prakasam dt. Pin code 523316
  • J. Akhila B. Pharmacy. Dr. Samuel George Institute Of Pharmaceutical Sciences Tarlupadu Road ,Markapur , Prakasam dt. Pin code 523316
  • M.Prabhavathi B. Pharmacy. Dr. Samuel George Institute Of Pharmaceutical Sciences Tarlupadu Road ,Markapur , Prakasam dt. Pin code 523316
  • Ch.Hanumantha Revathi B. Pharmacy. Dr. Samuel George Institute Of Pharmaceutical Sciences Tarlupadu Road ,Markapur , Prakasam dt. Pin code 523316

Abstract

Anti arthritic Herbal chocolate it is selected by medicinal herbs with proven anti inflammatory and antioxidant property such as Turmeric ( Curcuma Longa), Ginger (Zingiber officinale), Ashwagandha (Withania Somnifera) they are rich in flavonoids.They can enhance therapeutic efficacy through the synergestic antioxidant activity while improve patient safety to pleasant or good taste of chocolate. It is easy to chew and absorb easily in every humans. The formulated chocolate show significant inhibition of protein denaturation indicate potent antiarthritic potential.The formulations are evaluated by stability invitro antiarthritic acting protein denaturation and membrane stabilization assays.It is derived from the cocoa mixed fat. Sesame is herbal drug having some medicinal properties like anti arthritis property, antioxidant property. It can prevent rheumatoid arthritis Sesame used to improve the blood pressure and this sesame we have to formulate the chocolate for the extraction process. So, it is patient friendly and approach for manage the arthritis.

Keywords:

Sesame, antioxidant property, flavonoids, chocolate, ayurveda

DOI

https://doi.org/10.37022/wjcmpr.v7i3.375

References

1. Gravina SA, Yep GL, Khan M. Human biology of taste. Saudi Med J. 2013;33(3):217-22.

2. Ranasinghe P, Pigera S, Premakumara GS, Galappaththy P, Constantine GR, Katulanda P. Medicinal properties of “true” cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complement Altern Med. 2013;13:275.

3. Pandey G, Madhuri S. Pharmacological activities of Ocimum sanctum (Tulsi): a review. Int J Pharm Sci Rev Res. 2010;5(1):61-6.

4. Palpu P, Rawat AKS, Rao CV, Ojha SK, Reddy GD. U.S. Patent No. 7,247,322. Washington (DC): U.S. Patent and Trademark Office; 2007.

5. Ahmad V. A practical book of pharmacognosy and phytochemistry. 2021.

6. Sethi P. Quantitative analysis of pharmaceutical formulation. 1996.

7. SLD. A practical book of Pharmacognosy and Phytochemistry II. 2023.

8. Yogesh S, Kolekar S, More A, Harinath N. Formulation and evaluation of pediatric herbal chocolate. J Biomed Pharm Sci. 2021;8(6):458-504.

9. Chaudhari S, Devare R, Dewang P, Patil V, Patil A, Pawar S. Chocolate formulation as drug delivery system. Indian J Drugs. 2018;6(2):136-41.

10. Devi SL, editor. A practical book of Pharmacognosy and Phytochemistry II. 2023. p. 45-50.

11. Yogesh S, Kolekar SA, More AA, Harinath N. Formulation and evaluation of pediatric herbal chocolate. J Biomed Pharm Sci. 2021;8(6):458-504.

12. Mayank S, Jain D. Chocolate formulation as drug delivery system for pediatrics. Indones J Pharm. 2012;23(4):216-24.

13. Chaudhari SA, Devare RR, Dewang PS, Patil VB, Patil AM, Pawar SP, et al. Chocolate formulation as drug delivery system. Indian J Drugs. 2018;6(2):136-41.

14. Sunil KR, Mounika A. Design and fabrication of medicated chocolate formulation by chocolate drug delivery system. Int J Curr Pharm Res. 2017;9(5):128-33.

15. Rupa S, Baquee AA, Kumar BJ. Pharmacognostical evaluation of Terminalia arjuna bark on different marketed samples. Der Pharm Lett. 2014;6(3):299-303.

16. Sethi P. Identification of drugs in pharmaceutical formulations by TLC. 2014.

17. Identification of drugs in pharmaceutical formulations by TLC. 2541.

18. Pawar P, Bakliwal A, Talele S, Jadhav A. Formulation and evaluation of herbal chocolate as nervine tonic. J Pharm Sci Res. 2019;11(5):1808-13.

19. PS. Quantitative analysis of drugs in pharmaceutical formulations. 1996. Ahmad V. A practical book of pharmacognosy and phytochemistry. 2021.

20. Sethi P. Quantitative analysis of pharmaceutical formulation. 1996. Varsha Tiwari D, Ahmad. SLD. A practical book of Pharmacognosy and Phytochemistry II. 2023.

21. Yogesh S, Kolekar S, More A, Harinath N. Formulation and evaluation of pediatric herbal chocolate. J Biomed Pharm Sci. 2021;8(6):458-504.

22. Mayank S, Jain D. Chocolate formulation as drug delivery system for pediatrics. Indones J Pharm. 2012;23(4):216-24.

23. Chaudhari S, Devare R, Dewang P, Patil V, Patil A, Pawar S. Chocolate formulation as drug delivery system. Indian J Drugs. 2018;6(2):136-41.

24. Sunil K, Mounika A. Design and fabrication of medicated chocolate formulation by chocolate drug delivery system. Int J Curr Pharm Res. 2017;9(5):128-33.

25. Rupa S, Baquee A, Kumar B. Pharmacognostical evaluation of Terminalia arjuna bark on different marketed samples. Der Pharm Lett. 2014;6(3):299-303.

Published

2025-11-19
Statistics
Abstract Display: 62
PDF Downloads: 40
Dimension Badge

How to Cite

1.
Formulation and evaluation of antiarthritic herbal chocolate: a review. World Journal of Current Med and Pharm Research [Internet]. 2025 Nov. 19 [cited 2025 Dec. 30];7(3). Available from: https://wjcmpr.org/index.php/journal/article/view/375

Issue

Section

Review Articles

How to Cite

1.
Formulation and evaluation of antiarthritic herbal chocolate: a review. World Journal of Current Med and Pharm Research [Internet]. 2025 Nov. 19 [cited 2025 Dec. 30];7(3). Available from: https://wjcmpr.org/index.php/journal/article/view/375